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Electrochemical study of interactions between DNA and viologen‐thiol self‐assembled monolayers
Author(s) -
Li Jinghong,
Cheng Guangjin,
Dong Shaojun
Publication year - 1997
Publication title -
electroanalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.574
H-Index - 128
eISSN - 1521-4109
pISSN - 1040-0397
DOI - 10.1002/elan.1140091106
Subject(s) - viologen , monolayer , electrochemistry , thiol , chemistry , self assembled monolayer , dna , photochemistry , nanotechnology , combinatorial chemistry , materials science , organic chemistry , electrode , biochemistry
We investigated the binding characteristics of double‐stranded DNA to self‐assembled monolayers (SAMs) containing viologen groups formed on the surface of gold electrodes via Au–S bonds. The positive charged and hydrophobic surfaces of the viologen SAMs modified gold electrodes are suitable to bind strongly with DNA, whose interactions to solution DNA and adsorbed DNA both lead to positive shifts (22.5 mV and 65 mV, respectively) in the first redox potential of viologen centers, indicating that the main interaction is from a hydrophobic interaction. Meanwhile, the binding of DNA strongly affects the kinetics of electron transfer of the viologen group so that the separation of anodic and cathodic peak potentials becomes larger and the heterogeneous electron transfer constant becomes smaller.