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Advances in electrochemical immunosensors
Author(s) -
Skládal Petr
Publication year - 1997
Publication title -
electroanalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.574
H-Index - 128
eISSN - 1521-4109
pISSN - 1040-0397
DOI - 10.1002/elan.1140091002
Subject(s) - electrochemistry , chemistry , chromatography , computer science , electrode
The developments in the field of electrochemical immunosensors and immunoassays are reviewed. The enzyme labels suitable for amperometric, potentiometric and conductimetric detection are mentioned. Indirect immunosensors (i.e., that involving enzymatic or electroactive labels) use either heterogeneous or homogeneous formats. Immunoelectrodes are based on conventional electrodes, semiconductor devices are represented by ISFETs and light addressable potentiometric sensors (LAPS). Direct label‐free monitoring of immunoreactions is demonstrated on capacitance systems and pulsed detection using polypyrrole‐modified electrodes. The approaches to regeneration of sensing surfaces are discussed. Examples are given on applications of electrochemical immunodevices in clinical medicine and in environmental monitoring.