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pHh‐dependent permselectivity of the fibrinogen‐modified carbon paste electrode
Author(s) -
El Rhazi Mama,
Randriamahazaka Hyacinthe N.,
Nigretto JeanMaxime
Publication year - 1997
Publication title -
electroanalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.574
H-Index - 128
eISSN - 1521-4109
pISSN - 1040-0397
DOI - 10.1002/elan.1140090510
Subject(s) - chemistry , redox , isoelectric point , carbon paste electrode , electrochemistry , electrode , selectivity , inorganic chemistry , cationic polymerization , carbon fibers , organic chemistry , materials science , catalysis , cyclic voltammetry , composite material , composite number , enzyme
The modification of carbon paste matrices with fibrinogen is reported. The effect of the pH of the solution on the CV peak currents of positively or negatively charged redox analytes was examined at the fibrinogen‐modified carbon paste electrode. In the presence of the coating, pH‐dependent selectivity in electrochemical detection of charged species was demonstrated depending on the sign of the supported charge. Above the isoelectric pH attributed to the immobilized protein (5.5), the current response of anionic redox probes [Fe(CN) 6 3− /Fe(CN) 6 4− ] was impeded while the response was almost totally restored below this pH. Opposite trends were observed with the Ru(NH 3 ) 6 3+ /Ru(NH 3 ) 6 2+cationic redox analytes.