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Amperometric biosensors based on NAD(P)‐dependent dehydrogenase enzymes
Author(s) -
Lobo Maria Jesús,
Miranda Arturo J.,
Tuñón Paulino
Publication year - 1997
Publication title -
electroanalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.574
H-Index - 128
eISSN - 1521-4109
pISSN - 1040-0397
DOI - 10.1002/elan.1140090302
Subject(s) - biosensor , amperometry , nad+ kinase , dehydrogenase , cofactor , nicotinamide adenine dinucleotide , chemistry , enzyme , combinatorial chemistry , nicotinamide , electrochemistry , biochemistry , electrode
This review deals with the use of pyridine‐nucleotide dependent dehydrogenase enzymes in amperometric biosensor design. The electrochemistry of the nicotinamide coenzymes, their mechanism and the challenges associated with their direct oxidation on solid electrodes are discussed. In addition, a survey of the different solutions proposed in the literature for addressing these problems and some of their applications are presented.