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Dipyridamole plastic membrane electrodes based on individual and mixed ion‐exchangers of dipyridamolium phosphotungstate and tetraphenylborate
Author(s) -
Issa Yousry M.,
Rizk Mahmound S.,
Shoukry Adel F.,
ElNashar Rasha M.
Publication year - 1997
Publication title -
electroanalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.574
H-Index - 128
eISSN - 1521-4109
pISSN - 1040-0397
DOI - 10.1002/elan.1140090117
Subject(s) - tetraphenylborate , potentiometric titration , dipyridamole , sodium tetraphenylborate , chemistry , electrode , ion selective electrode , membrane , electroanalytical method , selectivity , ion exchange , standard addition , isothermal process , inorganic chemistry , analytical chemistry (journal) , nuclear chemistry , chromatography , ion , detection limit , organic chemistry , medicine , biochemistry , radiology , catalysis , physics , thermodynamics
Dipyridamole (Dp) selective PVC membrane based on dipyridamolium phosphotungstate (Dp‐PTA), dipyridamolium tetraphenylborate (Dp‐TPB) and a mixture of both (Dp‐PTA/TPB) were prepared. The electrodes displayed a linear response over the concentration range 6.3 × 10 −6 –1.0 × 10 −1 mol dm −3 dipyridamole hydrochloride (DpCI). The working pH ranges of the above electrodes were 2.0–7.5, 2.0–7.5 and 2.0–7.0 and their isothermal coefficients were 0.00096, 0.00010 and 0.00144 V/°C, respectively. The electrodes showed good selectivity to DpCI with respect to many inorganic cations, sugars and amino acids. Potentiometric titration and standard additions methods were used to determine DpCI in pure solutions and in pharmaceutical preparations with high accuracy and precision.