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Determination of tin( II ) in pharmaceuticals by amperometric oxidation after complexation with tropolone
Author(s) -
Boutakhrit K.,
Quarin G.,
Özkan S. A.,
Kauffmann J.M.
Publication year - 1996
Publication title -
electroanalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.574
H-Index - 128
eISSN - 1521-4109
pISSN - 1040-0397
DOI - 10.1002/elan.1140080816
Subject(s) - tropolone , tin , chemistry , detection limit , cyclic voltammetry , amperometry , electrode , voltammetry , inorganic chemistry , electrochemistry , nuclear chemistry , chromatography , organic chemistry
Inorganic tin( II ) was determined, rapidly and selectively in the presence of tin( IV ), by electrooxidation after complexation with tropolone (2‐hydroxy‐2,4,6‐cycloheptatrienone). By cyclic voltammetry, the tin( II )‐tropolone complex showed a well‐defined irreversible oxidation peak which occurred at −0.014 V ( vs. Ag/AgCI) at the glassy carbon electrode in 0.05 molL −1 acetate buffer pH 5.5. The determination of Sn II has been realized using FIA and by poising the electrode at +0.1 V. A linear relationship was obtained between peak current and tin( II ) in the concentration range 0.25–20 μmolL −1 . The detection limit was 0.1 μmolL −1 and the RSD calculated by injection of a 5 μmolL −1 tin( II ) solution was 1.5% ( n = 10).The optimization of several experimental parameters bas been realized and the influence of many cations and possible interfering species encountered in radiopharmaceuticals and in dental gels has been investigated. The method was applied to the determination of tin( II ) in dental gels.