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Electrochecmical biosensors for DNA sequence detection
Author(s) -
Mikkelsen Susan R.
Publication year - 1996
Publication title -
electroanalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.574
H-Index - 128
eISSN - 1521-4109
pISSN - 1040-0397
DOI - 10.1002/elan.1140080104
Subject(s) - biosensor , computational biology , dna , sequence (biology) , nanotechnology , chemistry , biology , biochemistry , materials science
A review of reported biosensors for the sequence‐selective detection of analyte DNA sequences shows that signal transduction based on electrogenerated chemiluminescence, potentiometry and voltammetry are all capable of detecting analyte DNA at attomole levels. In contrast, optical and piezoelectric transducers detect DNA at picomole and femtomole levels, respectively. The principles and applications of these promising electrochemical DNA biosensors are described and discussed.