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Flow injection potentiometric determination of harmine and harmaline hallucinogens
Author(s) -
Hassan Saad S. M.,
Elnemma Eman M.,
Hamada Marawan A.
Publication year - 1995
Publication title -
electroanalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.574
H-Index - 128
eISSN - 1521-4109
pISSN - 1040-0397
DOI - 10.1002/elan.1140070711
Subject(s) - harmaline , harmine , flow injection analysis , potentiometric titration , detection limit , chromatography , chemistry , linear range , hallucinogen , analytical chemistry (journal) , matrix (chemical analysis) , electrode , psychology , neuroscience , psychiatry , biology
Flow injection analysis (FIA) systems incorporating potentiometric sensors for harmine and harmaline hallucinogens are described. The sensors are based on the use of harmine and harmaline tetraphenylborate or reineckate as electroactive compounds dispersed in plasticized PVC matrix. Laboratory‐build flow‐through sandwich cell equipped with silver disk coated with the sensing material is used as a detector in a low dispersion FIA system. The detector exhibits fast and linear response over the concentration range 10 −2 −10 −6 M harmine or harmaline with a detection limit of 2 μg/mL (for 100 μL samples). Operational pH ranges from 3 to 8, sampling rate is 80 per hour and the precision is typically ±0.6%. Recovery and reproducibility data agree fairly well with those obtained by gas–liquid chromatography.