Amperometric glucose biosensors based on an osmium (2 + /3 + ) redox polymer‐mediated electron transfer at carbon paste electrodes

Four glucose sensors have been developed by modifying carbon paste electrodes with glucose oxidase as a biocomponent and a conducting redox osmium‐polymer as the mediating compound. The enzyme was immobilized by crosslinking with glutaraldehyde and bovine serum albumin in three modifications of electrodes and physical adsorption in one electrode. The optimal concentrations of the modifying compounds were determined and the response of the sensors to 2–20 mM glucose were characterized. The influence of pH, temperature, interferences, and storage on the responses of the sensors were investigated.