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Electrochemical study of pyrazolone derivatives at the liquid/liquid interface
Author(s) -
Wang Erkang,
Wang Hanming,
Yu Zemu
Publication year - 1994
Publication title -
electroanalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.574
H-Index - 128
eISSN - 1521-4109
pISSN - 1040-0397
DOI - 10.1002/elan.1140061117
Subject(s) - nitrobenzene , pyrazolone , electrochemistry , cyclic voltammetry , protonation , chemistry , cathodic protection , proton , voltammetry , anode , inorganic chemistry , organic chemistry , electrode , catalysis , ion , physics , quantum mechanics
Pyrazolone derivatives, such as antipyrine, aminopyrine, and 4‐aminoantipyrine, can transfer across the water/nitrobenzene interface to produce a pair of well‐defined symmetric, reversible anodic‐cathodic peaks by cyclic voltammetry. The transfer mechanism has been studied as a result of the formation of complex of related pyrazolone derivatives with a proton. The protonated complex formed then transferred across the water/nitrobenzene interface. The effect of drugs' structure on the transfer behavior was discussed and parameters related to interfacial behavior were determined.