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Adsorptive stripping voltammetric determination of folic acid in pharmaceutical preparations
Author(s) -
Szczepaniak W.,
Ren M.
Publication year - 1994
Publication title -
electroanalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.574
H-Index - 128
eISSN - 1521-4109
pISSN - 1040-0397
DOI - 10.1002/elan.1140060524
Subject(s) - pellets , chemistry , adsorptive stripping voltammetry , stripping (fiber) , relative standard deviation , folic acid , chromatography , supporting electrolyte , electrolyte , voltammetry , detection limit , electrochemistry , electrode , materials science , medicine , composite material
An adsorptive stripping voltammetric (AdSV) procedure is proposed for determination of folic acid (FA) in cores and coated pellets of Hemofer (FA/iron tablet). The adsorptive stripping response was evaluated with respect to the electrolyte solution, the accumulation time and potential, and the concentration dependence. The relationship between i p and FA concentration was linear over the range 1 × 10 −8 to 5 × 10 −7 M FA. The conditions of cores and pellets preparation for analysis were established. The relative standard deviation is 2.4% for a content of FA of 0.35 mg per core ( n = 5).