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Neuronal biosensors: A progress report
Author(s) -
Leech Dónal,
Rechnitz Garry A.
Publication year - 1993
Publication title -
electroanalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.574
H-Index - 128
eISSN - 1521-4109
pISSN - 1040-0397
DOI - 10.1002/elan.1140050203
Subject(s) - biosensor , analyte , microelectrode , chemoreceptor , multielectrode array , nanotechnology , biochemical engineering , chemistry , materials science , receptor , chromatography , electrode , biochemistry , engineering
A review of the progress of research in the development of intact chemoreceptor‐based biosensors is presented. These sensors utilize the chemosensing ability of the antennules of various decapod crustacea to sensitively and selectively detect chemical stimulants. Suction microelectrodes attached to the antennular nerve fibers are used to detect action potential firing upon binding of the stimulant to the receptor, allowing quantitation of the analyte. Recent developments in the use of different species and in improvements in experimental setup, data handling procedures, and sensor lifetimes are reported.