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Assessment of sodium‐selective ion‐selective electrodes based on methyl ketone derivative of p‐tert ‐butylcalix[4]arene
Author(s) -
TeltingDiaz Martin,
Diamond Dermot,
Smyth Malcolm R.,
Seward Eileen M.,
McKervey Anthony M.
Publication year - 1991
Publication title -
electroanalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.574
H-Index - 128
eISSN - 1521-4109
pISSN - 1040-0397
DOI - 10.1002/elan.1140030421
Subject(s) - ionophore , polyvinyl chloride , sodium , chemistry , detection limit , electrode , potassium , inorganic chemistry , sodium tetraphenylborate , ketone , selectivity , ether , ion selective electrode , ion exchange , nuclear chemistry , ion , membrane , chromatography , organic chemistry , catalysis , biochemistry
The performance of a newly synthesized tetramethyl ketone calyx [4]arene ionophore in ion‐selective electrodes has been investigated. Optimization of the plasticized polyvinyl chloride membrane composition has produced electrodes that exhibit a Nernstian response for sodium ions. The best general characteristics exhibited by the electrodes were found when the ionophore mixed with 2‐nitrophenyl octyl ether as plasticizing agent, and potassium tetrakis ( p ‐chlorophenyl) rate as ion exchanger. Selectivity studies carried out with the electrode have shown excellent discrimination for sodium against potassium and lithium ions. In addition, the electrode displays a rapid response time, a detection limit be low 10 −6 M for sodium, and a working life of at least 4 months. Determinations of sodium in plasma patient samples have been performed and the results obtained compared to those from flame photometry and two commercial clinical analyzers.