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Electrochemical behavior of spiroplatin at carbon paste and platinum electrodes
Author(s) -
Mebsout F.,
Kauffmann J.M.,
Patriarche G. J.,
Vereecken J.,
Christian G. D.
Publication year - 1989
Publication title -
electroanalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.574
H-Index - 128
eISSN - 1521-4109
pISSN - 1040-0397
DOI - 10.1002/elan.1140010311
Subject(s) - platinum , electrode , inorganic chemistry , electrochemistry , chloride , chemistry , scanning electron microscope , carbon fibers , solvent , metal , redox , materials science , catalysis , organic chemistry , composite material , composite number
The voltammetric behavior of the hydrolyzed platinum(II) antitumor drug spiroplatin has been investigated at carbon paste and platinized platinum electrodes. The compound is oxidized to the corresponding platinum(IV) species at positive potentials near the solvent oxidation potential. On reversal of the potential scan, two 2‐electron reduction steps occur on the carbon paste electrode, resulting in formation of platinum metal, as confirmed by scanning electron microscopy. In the presence of chloride, different reduction peaks associated with the formation of chloro structures are observed. These depend on the chloride ion concentration. The oxidation‐reduction steps become more reversible at the platinum electrode. The nature of the oxidized species and the amount of platinum deposit were found to be related to the concentration of free chloride ions. Because the carbon paste electrode has the ability to differentiate the different oxidized forms upon reduction, its use is recommended for studying these compounds.