Premium
Facile N ‐Formylation of Amines on Magnetic Fe 3 O 4 −CuO Nanocomposites
Author(s) -
Mishra Kanchan,
Datta Khanal Hari,
Rok Lee Yong
Publication year - 2021
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.202100872
Subject(s) - formylation , chemistry , catalysis , mesoporous material , nanocomposite , formic acid , nanoparticle , x ray photoelectron spectroscopy , heterogeneous catalysis , magnetic nanoparticles , copper , chemical engineering , inorganic chemistry , nuclear chemistry , organic chemistry , engineering
A facile, eco‐friendly, efficient, and recyclable heterogeneous catalyst is synthesized by immobilizing copper impregnated on mesoporous magnetic nanoparticles. The surface chemistry analysis of Fe 3 O 4 −CuO nanocomposites (NCs) by XRD and XPS demonstrates the synergistic effect between Fe 3 O 4 and CuO nanoparticles, providing mass‐transfer channels for the catalytic reaction. TEM images clearly indicate the impregnation of CuO onto mesoporous Fe 3 O 4 . This hydrothermally synthesized eco‐friendly and highly efficient Fe 3 O 4 −CuO NCs are applied as a magnetically retrievable heterogeneous catalyst for the N ‐formylation of wide range of aliphatic, aromatic, polyaromatic and heteroaromatic amines using formic acid as a formylating agent at room temperature. The catalytic activity of the NCs for N ‐formylation is attributable to the synergistic effect between Fe 3 O 4 and CuO nanoparticles. The N ‐formylated product is further employed for the synthesis of biologically active quinolone moieties.