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Cover Feature: Recent Developments in Enantioselective Organocatalytic Cascade Reactions for the Construction of Halogenated Ring Systems (Eur. J. Org. Chem. 29/2021)
Author(s) -
Maria Faisca Phillips Ana,
Pombeiro Armando J. L.
Publication year - 2021
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.202100731
Subject(s) - chemistry , enantioselective synthesis , cascade , combinatorial chemistry , ring (chemistry) , cascade reaction , organocatalysis , feature (linguistics) , atom economy , cover (algebra) , chirality (physics) , reagent , computational chemistry , stereochemistry , nanotechnology , organic chemistry , catalysis , engineering , philosophy , physics , mechanical engineering , linguistics , chiral symmetry breaking , materials science , chromatography , quantum mechanics , quark , nambu–jona lasinio model
The Cover Feature shows three examples of cascade reactions leading to chiral halogenated cyclic molecules. The multiple reactions that take place in succession (cascade‐like) once the reagents are mixed, provide a sustainable, atom‐, step‐ and labor‐efficient way to create chirality and molecular complexity. Easy‐to‐handle halogenating agents or synthetic building blocks and organocatalysts make this possible. The cascades of Buk Skradinski waterfall in the Krka National Park, Croatia illustrate the reaction pathways. More information can be found in the Minireview by A. M. Faisca Phillips and A. J. L. Pombeiro