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Electrochemical Scalable Sulfoxidation of Sulfides with Molecular Oxygen and Water
Author(s) -
Cheng Zhen,
Gao Xinglian,
Yao Lingling,
Wei Zhaoxin,
Qin Guohui,
Zhang Yonghong,
Wang Bin,
Xia Yu,
Abdukader Ablimit,
Xue Fei,
Jin Weiwei,
Liu Chenjiang
Publication year - 2021
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.202100610
Subject(s) - chemistry , electrochemistry , sulfoxide , molecular oxygen , combinatorial chemistry , oxygen , oxygen atom , dimethyl sulfoxide , organic chemistry , molecule , electrode
An efficient and chemoselective synthesis of sulfoxides through the electrooxidation of sulfides has been well developed. This protocol takes advantage of electricity as the terminal oxidant and of molecular oxygen and water as the oxygen atom sources. A variety of structurally diverse sulfoxide compounds are assembled in moderate to excellent yields. The scaled‐up reactions at 6–20 mmol show the good practicability and application potential of this methodology. A possible free radical mechanism has been proposed to rationalize the reaction procedure.