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Iron‐Catalyzed Synthesis of Pyrrole Derivatives and Related Five‐Membered Azacycles
Author(s) -
Wang Yeming,
Zhang Chaoqun,
Li Shizhe,
Liu Lihui
Publication year - 2021
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.202100586
Subject(s) - pyrrole , chemistry , catalysis , organic synthesis , organic chemistry , combinatorial chemistry
Pyrrole derivatives and their related five‐membered azacycles are a class of important five‐membered aromatic nitrogen heterocyclic compounds, and their synthesis attracted much the attention of organic chemists. Iron catalysis has been widely used in various organic transformations owing to their excellent catalytic activity, environmentally benign character, easy accessibility and low price. Over the past decades, a variety of facile and effective syntheses of pyrrole derivatives and related five‐membered azacycles based on iron catalysis has been reported. In this Minireview, the development of the iron‐catalyzed synthesis of pyrrole derivatives and their related five membered azacycles is reported in a comprehensive way, covering the literature up to March 2021.