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Versatile Electrochemical Oxidative C(sp 2 )−H Bond Selenylation of Resveratrol
Author(s) -
Lazzaris Maika J.,
Martins Guilherme M.,
Xavier Fernando R.,
Braga Antonio L.,
Mendes Samuel R.
Publication year - 2021
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.202100568
Subject(s) - chemistry , electrolysis , electrochemistry , electrolyte , oxidative phosphorylation , supporting electrolyte , resveratrol , electrosynthesis , transition metal , electrolytic cell , combinatorial chemistry , organic chemistry , catalysis , electrode , biochemistry
A simple and environmentally benign procedure for electrochemical oxidative mono‐ and bis‐selenylation of the resveratrol C(sp 2 )−H bond was developed. Driven by galvanostatic electrolysis in an undivided cell, it provided efficient transformation under oxidant‐, base‐, and transition metal‐free conditions, in an open system at room temperature. With satisfactory functional group compatibility, it required a substoichiometric amount of NaI, which acted as an electrolyte and mediator.