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Asymmetric Organocatalysis in Deep Eutectic Solvents
Author(s) -
Alonso Diego A.,
Burlingham SarahJayne,
Chinchilla Rafael,
Guillena Gabriela,
Ramón Diego J.,
Tiecco Matteo
Publication year - 2021
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.202100385
Subject(s) - organocatalysis , enantioselective synthesis , eutectic system , chemistry , organic chemistry , combinatorial chemistry , catalysis , alloy
The recent advances in asymmetric organocatalysis using eutectic mixtures as a reaction medium are revised in this mini‐review. In addition, the first enantioselective transformations using chiral eutectic solvents, which play the role of a green medium and organocatalyst, are described. In this minireview we intend to deepen not only in the synthetic aspects of asymmetric organocatalysis in eutectic mixtures, but also in the fundamental issues that seem to be essential for a successful development of this promising, and at the same time challenging, methodology.