Rhodium‐Catalyzed [3+2]‐Annulation of  ortho‐ Diazoquinones with Enol Ethers: Diversity‐Oriented Total Synthesis of Aflatoxin B 2 | Zendy

Paymode Dinesh J. | Zendy; Sharma Indrajeet | Zendy

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Rhodium‐Catalyzed [3+2]‐Annulation of ortho‐ Diazoquinones with Enol Ethers: Diversity‐Oriented Total Synthesis of Aflatoxin B 2

Author(s) -

Paymode Dinesh J.,

Sharma Indrajeet

Publication year - 2021

Publication title -

european journal of organic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.825

H-Index - 155

eISSN - 1099-0690

pISSN - 1434-193X

DOI - 10.1002/ejoc.202100186

Subject(s) - annulation , chemistry , enol , total synthesis , rhodium , catalysis , natural product , enol ether , substrate (aquarium) , aflatoxin , domino , organic chemistry , stereochemistry , combinatorial chemistry , oceanography , geology , food science

A simple and efficient approach for synthesizing substituted and fused polycyclic 2,3‐dihydrobenzofurans has been developed through a Rh‐catalyzed [3+2]‐annulation of ortho ‐diazoquinones with enol ethers. This methodology has a broad substrate scope and has been employed for the concise total synthesis of natural product aflatoxin B 2 .

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