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DMAP Mediated Efficient Construction of Functionalized Chromenes through One‐Pot Reaction of para ‐Quinone Methides with Allenoates
Author(s) -
Song Zefeng,
Jia Yuping,
Zhang Daizhou,
Wang De
Publication year - 2021
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.202100112
Subject(s) - chemistry , quinone methide , quinone , cascade reaction , cascade , reaction conditions , reaction mechanism , combinatorial chemistry , michael reaction , organic chemistry , catalysis , chromatography
A novel DMAP‐mediated Rauhut‐Currier/ oxa ‐Michael addition cascade reaction of hydroxylphenyl‐substituted para ‐quinone methide with allenoate was reported for the first time. A series of functionalized chromenes were successfully obtained with moderate to good yields under this one‐pot cascade reaction. The chromene products could be easily transformed into different derivatives and a plausible mechanism was proposed to elucidate this novel reaction.