Rh(III)‐Catalyzed C−H Activation/Annulation of Aryl Hydroxamates with CF 3 ‐Containing  α ‐Propargyl  α ‐Amino Acid Derivatives | Zendy

Vorobyeva Daria V. | Zendy; Petropavlovskikh Dmitry A. | Zendy; Godovikov Ivan A. | Zendy; Nefedov Sergey E. | Zendy; Osipov Sergey N. | Zendy

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Rh(III)‐Catalyzed C−H Activation/Annulation of Aryl Hydroxamates with CF 3 ‐Containing α ‐Propargyl α ‐Amino Acid Derivatives

Author(s) -

Vorobyeva Daria V.,

Petropavlovskikh Dmitry A.,

Godovikov Ivan A.,

Nefedov Sergey E.,

Osipov Sergey N.

Publication year - 2021

Publication title -

european journal of organic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.825

H-Index - 155

eISSN - 1099-0690

pISSN - 1434-193X

DOI - 10.1002/ejoc.202100040

Subject(s) - chemistry , annulation , propargyl , pharmacophore , aryl , catalysis , amino acid , stereochemistry , medicinal chemistry , organic chemistry , alkyl , biochemistry

A series of new orthogonally protected α ‐CF 3 ‐substituted α ‐amino carboxylates, and α‐amino phosphonates decorated with pharmacophore isoquinolone core has been elaborated through the Rh(III)‐catalyzed C−H activation/annulation of aryl hydroxamates with propargyl‐containing α ‐amino acid derivatives and their phosphorus analogues.

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