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Photochemical Reaction of N , N ‐Dimethylanilines with N‐Substituted Maleimides Utilizing Benzaldehyde as the Photoinitiator
Author(s) -
Nikitas Nikolaos F.,
Theodoropoulou Maria A.,
Kokotos Christoforos G.
Publication year - 2021
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.202001593
Subject(s) - photoinitiator , benzaldehyde , chemistry , photochemistry , adduct , organic chemistry , catalysis , polymer , monomer
Photoorganocatalysis constitutes a powerful domain of photochemistry and organic synthesis. The scaffold of pyrrolo[3,4‐c]quinolinoles exhibits interesting and potent inhibition against various enzymes, making them really promising pharmaceutical targets. Herein, we describe a photochemical methodology for the reaction of N , N ‐dimethylanilines with N‐substituted maleimides, utilizing benzaldehyde as the photoinitiator. A variety of substituted N , N ‐dimethylanilines and N‐substituted maleimides were converted into the corresponding adducts in moderate to high yields.