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Thiocarbamate‐directed Cp*Co(III)‐Catalyzed Olefinic C−H Amidation: Facile Access to Enamines with High ( Z )‐Selectivity
Author(s) -
Liang YaRu,
Si XiaoJu,
Zhang He,
Yang Dandan,
Niu JunLong,
Song MaoPing
Publication year - 2021
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.202001505
Subject(s) - thiocarbamate , chemistry , catalysis , selectivity , cobalt , combinatorial chemistry , medicinal chemistry , organic chemistry
A thiocarbamate‐directed Cp*Co(III)‐catalyzed C−H oxidative amidation of olefins is achieved to synthesize a series of enamines. The key feature of this protocol is the use of earth‐abundant cobalt as catalyst and thiocarbamate as directing group, which provides an efficient and simple manner to synthesize enamines in good yields with high ( Z )‐selectivity. This reaction proceeds smoothly under very mild conditions (rt and air), and a wide range of functionalized alkenes, as well as dioxazolones, were compatible with the standard reaction conditions.