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Metal‐free Photochemical Atom Transfer Radical Addition (ATRA) of BrCCl 3 to Alkenes
Author(s) -
Nikitas Nikolaos F.,
Voutyritsa Errika,
Gkizis Petros L.,
Kokotos Christoforos G.
Publication year - 2021
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.202001387
Subject(s) - chemistry , photochemistry , substrate (aquarium) , photoinitiator , atom (system on chip) , hydrogen atom , metal , radical , organic chemistry , group (periodic table) , oceanography , monomer , computer science , embedded system , geology , polymer
A simple, photochemical, and metal‐free protocol for the atom transfer radical addition (ATRA) of bromotrichloromethane onto various alkenes is described. Among a range of organic molecules, phenylglyoxylic acid proved to be the most suitable photoinitiator to promote a sustainable process for the addition of bromotrichloromethane to olefins. This photochemical atom transfer radical protocol can be expanded into a wide substrate scope of aliphatic olefins bearing various functional groups, leading to the corresponding products in good to excellent yields.