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Updating the CSIC Reaction (2003–2020)
Author(s) -
Dobrydnev Alexey V.,
MarcoContelles José
Publication year - 2021
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.202001330
Subject(s) - chemistry , carbanion , sulfonamide , sulfonate , intramolecular force , combinatorial chemistry , organic chemistry , sodium
Abstract Herein, we have updated the progress and developments of the Carbanion‐mediated Sulfonate (or Sulfonamide) Intermolecular Coupling, and Intramolecular Cyclization , abbreviated as CSIC reaction (CSICr), in the last seventeen years from the seminal review published in 2003 in this same Journal . CSICr has proven to be a useful and versatile synthetic tool, efficiently providing a number of open‐chain [alkane(sulfonamide)sulfonates] or cylic (sultams and sultones) synthetic intermediates or final products of high value in organic and medicinal chemistry.