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Overcoming the Hurdles and Challenges Associated with Developing Continuous Industrial Processes
Author(s) -
Baumann Marcus,
Moody Thomas S.,
Smyth Megan,
Wharry Scott
Publication year - 2020
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.202001278
Subject(s) - continuous flow , process development , process (computing) , flow chemistry , scale (ratio) , chemistry , biochemical engineering , engineering ethics , nanotechnology , management science , risk analysis (engineering) , computer science , process management , engineering , business , physics , materials science , quantum mechanics , operating system
Continuous flow chemistry is often viewed as a very simple concept on paper, however scientists with significant flow chemistry experience will highlight a number of challenges that need to be overcome. Critical for the successful development of any flow process is a high level of understanding of potential pitfalls that may be encountered. A collaborative and multi‐disciplinary team of chemists and chemical engineers is essential in the development of a process from lab scale through to production. This Minireview will identify and highlight relevant risks and their subsequent mitigation strategies to ensure successful flow processing.

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