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Recent Progress in Non‐Catalytic C–H Functionalization of Heterocyclic N ‐Oxides
Author(s) -
Kutasevich Anton V.,
Perevalov Valery P.,
Mityanov Vitaly S.
Publication year - 2021
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.202001115
Subject(s) - surface modification , chemistry , catalysis , homogeneous , organic synthesis , homogeneous catalysis , transition metal , combinatorial chemistry , organic chemistry , nanotechnology , materials science , physics , thermodynamics
Considerable attention holds on the chemistry and application of heterocyclic N ‐oxides due to their advantages as building‐blocks in organic synthesis and importance in biomedical research. On the other hand, in recent years the development of selective methods for constructing C–C, C–N, C–P, C–S, and C–O bonds via direct C–H functionalization has become especially demand in organic synthesis. These circumstances determine the significance of this minireview, which present recent advances in the field of C–H functionalization of heterocyclic N ‐oxides. Data on various type reactions which formal result is the replacement of a hydrogen atom in a heterocycle, with the exclusion of methods using heterogeneous and homogeneous catalysts based on transition metals, are summarized. Presented works for the last 15 years, since 2006.