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Recent Progress in the Asymmetric Syntheses of α‐Heterofunctionalized (Masked) α‐ and β‐Amino Acid Derivatives
Author(s) -
Eder Isabella,
Haider Victoria,
Zebrowski Paul,
Waser Mario
Publication year - 2021
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.202001077
Subject(s) - chemistry , enantioselective synthesis , combinatorial chemistry , amino acid , organocatalysis , catalysis , organic chemistry , nanotechnology , biochemistry , materials science
The asymmetric synthesis of α‐heterofunctionalized α‐ and β‐amino acid derivatives has been a heavily investigated topic over the last years, benefiting from the development of novel catalysis concepts as well as from the introduction of suited new precursor entities. Within this short review, we wish to give an illustrative overview of the most successfully applied concepts to access these targets, like asymmetric α‐heterofunctionalizations or asymmetric C–C‐bond forming reactions of already heterofunctionalized precursors.