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Front Cover: Electrochemical Selenation/Cyclization of Quinones: A Rapid, Green and Efficient Access to Functionalized Trypanocidal and Antitumor Compounds (Eur. J. Org. Chem. 29/2020)
Author(s) -
Kharma Ammar,
Jacob Claus,
Bozzi Ícaro A. O.,
Jardim Guilherme A. M.,
Braga Antonio L.,
Salomão Kelly,
Gatto Claudia C.,
Silva Maria Francilene S.,
Pessoa Claudia,
Stangier Maximilian,
Ackermann Lutz,
da Silva Júnior Eufrânio N.
Publication year - 2020
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.202001035
Subject(s) - front cover , chemistry , diphenyl diselenide , cover (algebra) , combinatorial chemistry , stereochemistry , organic chemistry , selenium , mechanical engineering , engineering
The Front Cover shows the power of electricity to mediate selenation reactions. In our image a Tesla static electricity generator, in honor of Nikola Tesla, was used to generate the electricity that enables the reaction between diphenyl diselenide and lapachol to prepare selenium‐containing lapachones. The rapid, green and efficient protocol avoids chemical oxidants and allows the synthesis of target molecules in a fast and reliable way. Our paper also describes compounds with activity against five cancer cell lines and Trypanosoma cruzi, the parasite that causes Chagas disease. More information can be found in the Full Paper by C. Jacob, L. Ackermann, E. N. da Silva Júnior et al.