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Synthesis of Spongidepsin and Analogs
Author(s) -
Ferrié Laurent,
Picot Ondine,
Guérinot Amandine,
Cossy Janine
Publication year - 2020
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.202001009
Subject(s) - natural product , stereochemistry , chemistry , combinatorial chemistry
Seven syntheses of (–)‐spongidepsin, a natural product isolated from Spongia sp . with moderate antiproliferative activity, are described and the different analogs obtained during these syntheses are reported. A comparison between the different syntheses has been achieved.