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Facile Synthesis of γ‐Ketonitriles in Water via C(sp 2 )–H Activation of Aromatic Aldehydes over Cu@g‐C 3 N 4 under Visible‐Light
Author(s) -
Rai Vijai K.,
Verma Fooleswar,
Bhardiya Smita R.,
Sheshma Harendra,
Rai Ankita,
Singh Manorama
Publication year - 2020
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.202000945
Subject(s) - chemistry , aldehyde , photocatalysis , acrylonitrile , visible spectrum , yield (engineering) , solvent , photochemistry , intermolecular force , nitrile , catalysis , organic chemistry , molecule , physics , optoelectronics , materials science , copolymer , metallurgy , polymer
A facile C(sp 2 )–H activation of aldehyde under visible‐light conditions using Cu@g‐C 3 N 4 as photocatalyst and water as solvent is reported. The envisaged method involves photocatalytic intermolecular Stetter reaction using differently substituted aldehydes and acrylonitrile to produce various γ‐keto nitriles in good to excellent yield (80–95 %) and 4–10 h at r.t. Operational simplicity, ambient reaction conditions, visible‐light condition, and application of the Cu@g‐C 3 N 4 as photocatalyst make the envisaged protocol an efficient and highly green alternative to the existing methods for synthesis of γ‐keto nitriles.