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Front Cover: Solid Phase Synthesis of Sulfonimidamide Pseudopeptides and Library Generation (Eur. J. Org. Chem. 25/2020)
Author(s) -
Chinthakindi Praveen K.,
Benediktsdottir Andrea,
Arvidsson Per I.,
Chen Yantao,
Sandström Anja
Publication year - 2020
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.202000882
Subject(s) - front cover , chemistry , solid phase synthesis , triphenylphosphine , combinatorial chemistry , peptide synthesis , sulfur , organic chemistry , cover (algebra) , peptide , catalysis , biochemistry , mechanical engineering , engineering
The Front Cover shows the combined world of solid‐phase peptide synthesis and sulfur chemistry on a background of a sulfur landscape. A peptide chain attached to a polymer resin is functionalized through formation of a sulfonamide and the magic touch of triphenylphosphine dichloride. The resulting sulfonimidamide pseudopeptides are thereafter released from the resin. The method allows easy generation of novel chemical libraries, useful in drug discovery. Graphic design by Andrea Benediktsdottir. More information can be found in the Full Paper by P. K. Chinthakindi, A Benediktsdottir, A. Sandström et al.