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Iridium‐Catalyzed Carbenoid Insertion of Sulfoxonium Ylides for Synthesis of Quinoxalines and β‐Keto Thioethers in Water
Author(s) -
Xu Yingying,
Huang Xin,
Lv Guanghui,
Lai Ruizhi,
Lv Songyang,
Li Jianglian,
Hai Li,
Wu Yong
Publication year - 2020
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.202000716
Subject(s) - carbene , chemistry , iridium , carbenoid , annulation , quinoxaline , catalysis , combinatorial chemistry , organic chemistry , medicinal chemistry , rhodium
Sulfoxonium ylides as safe carbene precursors are described for iridium‐catalyzed carbene insertions and annulation, providing a facile and green approach to access a variety of quinoxaline derivatives in water. This water‐mediated method also allows the preparation of β‐keto thioethers under mild condition.

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