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Radical‐Triggered Cyclization of Methylthio‐Substituted Alkynones: Synthesis of Diverse 3‐Alkylthiochromones
Author(s) -
Zheng Xiangyun,
Zhong Tianshuo,
Zhang Lei,
Chen Junyu,
Chen Zhiwei,
Jiang Xinpeng,
Yu Chuanming
Publication year - 2020
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.202000663
Subject(s) - chemistry , radical cyclization , combinatorial chemistry , organic chemistry
The efficient synthesis of diverse 3‐alkylthiochromone species through radical‐triggered cyclization of methylthio‐substituted alkynones is reported. This metal‐free protocol is compatible with a wide variety of radical donors under mild conditions, thus enabling the synthesis of various 3‐alkylthiochromones.