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Electrochemical Synthesis of 5‐Selenouracil Derivatives by Selenylation of Uracils
Author(s) -
Wang Qian,
Ma XianLi,
Chen YanYan,
Jiang CaiNa,
Xu YanLi
Publication year - 2020
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.202000637
Subject(s) - chemistry , electrochemistry , transformation (genetics) , transition metal , combinatorial chemistry , organic chemistry , catalysis , electrode , biochemistry , gene
A simple and efficient electrochemical selenylation of uracils in the presence of NH 4 I for the synthesis of 5‐selenouracils has been developed. This transformation was performed in the transition metal‐free, oxidant‐free, and aerobic conditions, providing a rapid and practical protocol to 5‐selenouracil derivatives.
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