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Copper‐Catalyzed Electrophilic Amination of Alkoxyarylsilanes
Author(s) -
Zhang Qian,
Hitoshio Kenshiro,
Saito Hayate,
Shimokawa Jun,
Yorimitsu Hideki
Publication year - 2020
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.202000562
Subject(s) - chemistry , amination , catalysis , electrophilic amination , copper , stoichiometry , electrophile , organic chemistry , electrophilic fluorination , combinatorial chemistry , activator (genetics) , biochemistry , gene
We report a copper‐catalyzed amination reaction between simple alkoxyarylsilanes and N ‐benzoyloxyamines. Silver fluoride serves as a stoichiometric base as well as an indispensable activator that allows the catalytic process to proceed. Multiply alkoxylated arylsilanes, such as trialkoxyarylsilanes and dialkoxyarylsilanes were transformed into the corresponding tertiary anilines under mild reaction conditions.