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A Concise Synthesis of the Key Tetrahydrofuran Moieties of Caruifolin A and EBC‐342
Author(s) -
Fernandes Rodney A.,
Bethi Venkati
Publication year - 2020
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.202000513
Subject(s) - chemistry , tetrahydrofuran , dihydroxylation , intramolecular force , furan , key (lock) , enantioselective synthesis , stereochemistry , combinatorial chemistry , organic chemistry , catalysis , ecology , solvent , biology
A common strategy for the concise synthesis of the key tetrahydrofuran moieties of caruifolin A and EBC‐342 is presented. Asymmetric dihydroxylation and intramolecular S N 2‐cyclization are key strategic reactions for the synthesis of the furan fragments.