Synthesis of Functionalized Bridged Bicyclic Sulfonamides with a Bridgehead Nitrogen Atom | Zendy

Blahun Oleksandr P. | Zendy; Melnychenko Heorhii | Zendy; Kuchkovska Yuliya O. | Zendy; Zhersh Serhii | Zendy; Tolmachev Andrey A. | Zendy; Grygorenko Oleksandr O. | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

Synthesis of Functionalized Bridged Bicyclic Sulfonamides with a Bridgehead Nitrogen Atom

Author(s) -

Blahun Oleksandr P.,

Melnychenko Heorhii,

Kuchkovska Yuliya O.,

Zhersh Serhii,

Tolmachev Andrey A.,

Grygorenko Oleksandr O.

Publication year - 2020

Publication title -

european journal of organic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.825

H-Index - 155

eISSN - 1099-0690

pISSN - 1434-193X

DOI - 10.1002/ejoc.202000314

Subject(s) - bicyclic molecule , chemistry , nitrogen atom , carboxylation , stereochemistry , combinatorial chemistry , organic chemistry , ring (chemistry) , catalysis

Two approaches to the synthesis of functionalized bridged bicyclic sulfonamides with a bridgehead nitrogen atom were developed. The target compounds were obtained either by introduction of a CH 2 SO 2 bridge into functionalized monocyclic substrates or by final‐step carboxylation of parent bicyclic cores. The described methods allowed preparation of the final products on a multigram scale.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research