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Carboxylation of Alkenyl Boronic Acids and Alkenyl Boronic Acid Pinacol Esters with CO 2 Catalyzed by Cuprous Halide
Author(s) -
Hong Junting,
Nayal Onkar S.,
Mo Fanyang
Publication year - 2020
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.202000288
Subject(s) - chemistry , pinacol , carboxylation , boronic acid , halide , catalysis , organic chemistry , yield (engineering) , boron , carbonylation , medicinal chemistry , carbon monoxide , materials science , metallurgy
A cuprous halide catalysed carboxylation of alkenyl boronic acids and alkenyl boronic acid pinacol esters under CO 2 , affording the corresponding α, β‐unsaturated carboxylic acids in good yield, has been developed. The potassium ( E )‐trifluoro(styryl)borate is also compatible with this reaction. This simple and efficient copper(I) catalytic system showed good functional group tolerance.