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Palladium‐Catalyzed [4+2] and [5+2] Annulation for the Synthesis of Tetrahydroquinolines and 1,4‐Benzoxazepines
Author(s) -
Zhang ZhaoFei,
Zhang Yan,
Zhang ChunLin,
Ye Song
Publication year - 2020
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.202000262
Subject(s) - chemistry , annulation , palladium , catalysis , malonate , diethyl malonate , propargyl , organic chemistry , combinatorial chemistry , stereochemistry , medicinal chemistry
Palladium‐catalyzed [4+2] and [5+2] annulations of propargyl carbonates with malonate‐tethered anilines and 2‐aminobenzylic alcohols were developed, giving the corresponding tetrahydroquinolines and 1,4‐benzoxazepines, respectively, in good to excellent yields.