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Front Cover: (Het)aryl Difluoromethyl‐Substituted β‐Alkoxyenones: Synthesis and Heterocyclizations (Eur. J. Org. Chem. 9/2020)
Author(s) -
Bugera Maksym Ya.,
Tarasenko Karen V.,
Kondratov Ivan S.,
Gerus Igor I.,
Vashchenko Bohdan V.,
Ivasyshyn Viktor E.,
Grygorenko Oleksandr O.
Publication year - 2020
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.202000039
Subject(s) - chemistry , front cover , aryl , chemical space , combinatorial chemistry , drug discovery , stereochemistry , organic chemistry , cover (algebra) , mechanical engineering , alkyl , engineering , biochemistry
The Front Cover shows (het)aryl difluoromethyl‐substituted β‐alkoxyenones, depicted as a bridge providing access to new areas of chemical space. In particular, heterocyclizations of these fluorinated bis‐electrophiles lead to compounds bearing a difluoro–CF 2 –(hetero)aryl motif – promising novel chemotypes for drug discovery. Inspiration from J. J. Grandville's illustration from Un Autre Mond (H. Fournier, Paris, 1844), as well as invaluable help of Mr. Serhii Gula and Ms. Vladyslava Prykhodko with artwork preparation are appreciated. More information can be found in the Full Paper by I. S. Kondratov, O. O. Grygorenko et al.