Premium
Cover Feature: Metal‐Free Visible‐Light‐Mediated Hydrotrifluoromethylation of Unactivated Alkenes and Alkynes in Continuous Flow (Eur. J. Org. Chem. 10/2020)
Author(s) -
Barthelemy AnneLaure,
Dagousset Guillaume,
Magnier Emmanuel
Publication year - 2020
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201901800
Subject(s) - chemistry , radical , photoredox catalysis , reagent , flow chemistry , cover (algebra) , feature (linguistics) , photochemistry , catalysis , combinatorial chemistry , organic chemistry , photocatalysis , mechanical engineering , linguistics , philosophy , engineering
The Cover Feature shows the combination of flow chemistry and photoredox catalysis for the hydroperfluoroalkylation of alkenes and alkynes. Organic dye (Rhodamine B) and green light promote this safe and scalable transformation. Perfluorinated sulfilimino iminiums, readily accessible reagents through a one‐pot multigram procedure, are used as source of radicals. Their modularity allows for the monofluoro‐, difluoro‐, trifluoro‐, and perfluoroalkylation of unsaturated systems. We choose the tubbing frontage of the French National Art Center Georges Pompidou to symbolize our flow reaction. More information can be found in the Communication by G. Dagousset, E. Magnieret al.