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Cover Feature: Lewis Base Catalysis Promoted Nucleophilic Substitutions – Recent Advances and Future Directions (Eur. J. Org. Chem. 1/2020)
Author(s) -
Huy Peter H.
Publication year - 2020
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201901798
Subject(s) - chemistry , lewis acids and bases , nucleophile , cover (algebra) , catalysis , base (topology) , combinatorial chemistry , stereochemistry , computational chemistry , organic chemistry , mechanical engineering , engineering , mathematical analysis , mathematics
The Cover Feature shows Lewis base catalyzed nucleophilic substitutions (SN) engaging non‐activated alcohols, carboxylic acids, aldehydes, and epoxides as substrates. In fact, S N ‐transformations are of fundamental significance in chemistry. Especially in the last decade, powerful catalytic approaches for S N ‐type C–C, C–N, C–O, and C–Cl bond formations have been implemented. The current review outlines modern concepts for catalytic S N ‐conversions and details novel Lewis base promoted methods. More information can be found in the Minireview by P. H. Huy et al.