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Diastereoselective sp3‐C–H Functionalization of Arylmethyl Ketones and Transformation of E ‐ to Z ‐Products Through Photocatalysis
Author(s) -
Rastogi Gaurav K.,
Deka Bhaskar,
Deb Mohit L.,
Baruah Pranjal K.
Publication year - 2020
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201901415
Subject(s) - chemistry , photocatalysis , reagent , microwave irradiation , eosin y , persulfate , catalysis , sulfoxide , surface modification , organic chemistry , irradiation , combinatorial chemistry , medicinal chemistry , photochemistry , physics , nuclear physics
We have developed an efficient metal‐free route for the synthesis of 1,4‐enedione derivatives under microwave irradiation by reacting easily available arylmethylketones with DMSO or diphenyl sulfoxide in the presence of TBAI and persulfate. The reaction is very clean and completes within very short time. All the reagents and catalysts are cheap and environmentally benign. In addition, the E ‐isomer of the products can easily be transformed into the Z ‐isomer by using eosin Y photocatalyst under the irradiation of white CFL.