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Chemoselective C–S/S–S Formation between Diaryl Disulfides and Tetraalkylthiuram Disulfides
Author(s) -
Peng Kang,
Zhu Hui,
Liu Xing,
Peng HanYing,
Chen JinQuan,
Dong ZhiBing
Publication year - 2019
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201901401
Subject(s) - chemoselectivity , chemistry , dithiocarbamate , aryl , selectivity , catalysis , combinatorial chemistry , base (topology) , organic chemistry , alkyl , mathematical analysis , mathematics
An efficient C–S/S–S formation for the chemoselective synthesis of aryl dithiocarbamate (C–S formation) and aryl dialkylcarbamo(dithioperoxo)thioate (S–S formation) was studied. The chemoselectivity could be controlled by modulating the reaction temperature, base, and catalyst. The transformation features a simple reaction, easily available starting materials, high selectivity and easy performance, showing its practical synthetic value for the preparation of some potential biologically or pharmaceutically active compounds.