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Synthetic Strategies towards the Synthesis of Oxyisocyclointegrin
Author(s) -
Smith Robert J.,
Hawkins Bill C.
Publication year - 2019
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201901294
Subject(s) - chemistry , flavones , combinatorial chemistry , stereochemistry , organic chemistry , nanotechnology , chromatography , materials science
Numerous natural products containing oxepine‐fused flavones have been isolated and reported over the last fifty years. This compound class typically possess anti‐proliferative and/or antibacterial properties. Herein we provide a full account of our original synthetic strategies along with further details of our ultimately successful approach to oxyisocyclointegrin.