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Electrochemical Coupling of Arylsulfonyl Hydrazides and Tertiary Amines for the Synthesis of β‐Amidovinyl Sulfones
Author(s) -
Kim HanSung,
Lee Sunwoo
Publication year - 2019
Publication title -
european journal of organic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.825
H-Index - 155
eISSN - 1099-0690
pISSN - 1434-193X
DOI - 10.1002/ejoc.201901277
Subject(s) - chemistry , electrochemistry , sulfoxide , sulfone , graphite , combinatorial chemistry , platinum , electrode , organic chemistry , polymer chemistry , catalysis
The reaction of arylsulfonyl hydrazides with tertiary amines provided β‐amidovinyl sulfones in good yields under mild electrochemical conditions. The reactions were carried out using an acid, in a solution of n Bu 4 NBF 4 in dimethyl sulfoxide in undivided cells with graphite‐platinum electrodes under a constant current. The arylsulfonyl hydrazides and tertiary amines were activated via a radical process by electrochemical oxidation and reacted to give the desired β‐amidovinyl sulfones.