Pd‐Catalyzed Allylation of Imines to Access α‐CF 3 ‐Substituted α‐Amino Acid Derivatives

We herein report a high yielding protocol for the direct α‐allylation of easily accessible trifluoropyruvate‐derived imines using Pd‐catalysis. The reaction gives access to a variety of different α‐allylated‐α‐CF 3 ‐amino acids in a straightforward manner, starting from commercially available trifluoropyruvate. We also provide a proof‐of‐concept for an enantioselective protocol (up to er = 75:25) by using chiral phosphane ligands.